

Kai’Sa vs Seraphine Counter Pick
Matchup Summary
What the Data Means
Kai’Sa is a marksman/mage hybrid, Seraphine a support/mage hybrid, and they meet in the ADC lane. Over 1,992 ranked games on patch 16.13.1, Kai’Sa closes out 43.5% of them. Sitting 6.5 points below the 50% line marks Seraphine as a genuine problem pick for Kai’Sa.
Kai’Sa and Seraphine overlap on physical damage, so itemisation converges rather than splits. Level-one bases: Kai’Sa 640 HP / 25 armour / 30 MR, Seraphine 570 / 26 / 30. Level 18 armour lands at 96 for Kai’Sa and 97 for Seraphine. Base attack damage is 59 against 50, so Kai’Sa wins the raw auto-attack exchange. Kai’Sa walks at 335 and Seraphine at 330, so Kai’Sa dodges skillshots a fraction easier.
Kai’Sa looks for Supercharge (E); Seraphine answers with High Note (Q). Ultimates decide the rest — Killer Instinct versus Encore.
With both sitting in ranged range (525 against 525), neither side gets a free poke pattern.
Sample size counts as much as the number — 1,992 games for Seraphine here. No hand-editing here — the Kai’Sa figures come straight from ranked play.
FAQ
No — current data marks this as a counter matchup: Seraphine has the statistical edge. Kai'Sa wins 43.5% of the recorded games.
43.5% from Kai'Sa's perspective, measured on patch 16.13.1.
1,992 ranked games at Emerald rank and above, across all regions.
The current Kai'Sa build — items, runes and skill order from the same data set — is on the Kai'Sa build page.