

Miss Fortune vs Vayne Counter Pick
Matchup Summary
What the Data Means
Vayne begins the game on 550 health, the lowest base value in the pairing, and she has to survive to the point where Silver Bolts and Final Hour take over. Across 2,175 games on patch 16.13.1, Miss Fortune prevents that often enough to hold 52.3%.
Both champions attack from 550 units, so there is no safety margin for the more fragile one. Double Up and Love Tap keep an opponent’s health moving downward without requiring an all-in, and Make It Rain slows a whole area, which answers a champion whose Night Hunter passive is about closing distance on nearby enemy champions quickly.
Vayne’s counterplay is real but demanding, and her difficulty rating of 8 against Miss Fortune’s 1 reflects the workload. Tumble repositions and empowers the next shot, Condemn knocks a target back and stuns it against terrain, and Final Hour layers attack damage, invisibility during Tumble and a reduced Tumble cooldown together. Executed properly, the third-hit percentage damage from Silver Bolts beats any health total.
What she brings into the early game is thin: 60 base attack damage against 55 and 330 movement speed against 325, but only 23 armour and no way to clear a wave from range. Pushing the wave and forcing her to farm under tower is the standard plan, since every minute she spends behind delays the scaling she depends on. Kit: Vayne.
FAQ
Yes — Miss Fortune holds the statistical advantage in this matchup. Miss Fortune wins 52.3% of the recorded games.
52.3% from Miss Fortune's perspective, measured on patch 16.13.1.
2,175 ranked games at Emerald rank and above, across all regions.
The current Miss Fortune build — items, runes and skill order from the same data set — is on the Miss Fortune build page.