Senna vs Karthus Counter Pick
Matchup Summary
What the Data Means
Two very different profiles meet in the ADC lane: Senna the support/marksman hybrid, Karthus the mage. 318 tracked games on 16.13.1 put Senna at a 44.3% win rate into Karthus. Sitting 5.7 points below the 50% line marks Karthus as a genuine problem pick for Senna.
With both sitting in ranged range (600 against 450), neither side gets a free poke pattern.
A missed Dawning Shadow from Senna hands Karthus the window to land Wall of Pain. Level six shifts things: Dawning Shadow on one side, Requiem on the other.
Shared damage type here — mixed for Senna as well as Karthus. Before items it is 530 HP, 25 armour, 30 MR for Senna; 620, 21, 30 for Karthus. By level 18 that becomes 2043 health and 93 armour for Senna against 2490 and 101 for Karthus. Base attack damage is 50 against 46, so Senna wins the raw auto-attack exchange. There is a movement gap too: 330 for Senna, 335 for Karthus.
Read 44.3% as a trend: 318 games is useful, not final. Everything comes from Emerald+ solo queue and refreshes without manual input.
FAQ
No — current data marks this as a counter matchup: Karthus has the statistical edge. Senna wins 44.3% of the recorded games.
44.3% from Senna's perspective, measured on patch 16.13.1.
318 ranked games at Emerald rank and above, across all regions.
The current Senna build — items, runes and skill order from the same data set — is on the Senna build page.